GastroDose

The TIMERx® technology is based on a customized, agglomerated hydrophilic complex that forms a controlled-release matrix upon compression. The matrix consists of two polysaccharides, xanthan and locust bean gum. Interactions between these components in an aqueous environment form a tight gel with a slowly-eroding core.

The following mechanistic illustration shows how the interactions between the polysaccharides form a matrix with the active compound. This system controls the rate of water ingress into the matrix and subsequent diffusion and release of the drug from the dosage form.



 

2008 Penwest Pharmaceuticals Co.
Terms and Conditions, Privacy Statement, & Safe Harbor