SyncroDose™ is a novel enabling technology that utilizes Penwest's TIMERx^® agglomerated hydrophilic matrix system to allow drugs to be delivered after predetermined lag times to coincide with the body's circadian rhythm pattern or to allow drugs to be delivered to different sites within the gastrointestinal tract.

A SyncroDose tablet consists of an inner core of drug and a surrounding compression coating containing TIMERx-based materials. Lag time is controlled by variations in the two polysaccharides, xanthan gum and locust bean gum.

SyncroDose works by controlling the rate of water ingress into the coating and subsequent erosion of the external polysaccharide-containing layer. The rate of release can be controlled by the modification of the coating layer.